One-pot synthesis of pyrroles using a titanium-catalyzed multicomponent coupling procedure

A straightforward one-pot multicomponent synthesis of polysubstituted pyrroles.

Polysubstituted pyrroles were efficiently synthesized in moderate yields by a one-pot multicomponent reaction starting from primary amines, ethyl glyoxalate and 2-bromoacetophenones in the presence of pyridine in refluxing acetonitrile. This methodology was utilized to synthesize a highly substituted benz[g]indole.

One-pot highly efficient synthesis of substituted pyrroles and N-bridgehead pyrroles by zinc-catalyzed multicomponent reaction.

A convenient zinc(II) chloride-catalyzed regioselective propargylation/amination/cycloisomerization process has been developed for the synthesis of substituted pyrrole derivatives from propargylic acetates, enoxysilanes and primary amines. Various aromatic and aliphatic propargylic acetates participate well in the reaction, providing the propargylation/amination/cycloisomerization products in g...

Mesolite catalyzed one pot synthesis of quinoline-3-carbonitrile derivatives

Natural mesolite type zeolite was collected, modified by sulfuric acid treatment and characterized by using Powder-X ray diffraction (XRD), Scanning electron microscopy (SEM), Energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR).Temperature programmed ammonia desorption (NH3-TPD), Brunauer-Emmer-Teller (BET) surface area analysis.  Modified dealuminat...

Mesolite catalyzed one pot synthesis of quinoline-3-carbonitrile derivatives

Natural mesolite type zeolite was collected, modified by sulfuric acid treatment and characterized by using Powder-X ray diffraction (XRD), Scanning electron microscopy (SEM), Energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR).Temperature programmed ammonia desorption (NH3-TPD), Brunauer-Emmer-Teller (BET) surface area analysis.  Modified dealuminat...

CuCl2 Catalyzed Solvent-free One Pot Synthesis of Dihydropyrimidinones